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  • Gastrointestinal Physiology : Development, Principles and Mechanisms of Regulation
    Gastrointestinal Physiology : Development, Principles and Mechanisms of Regulation

    This book offers one of the most comprehensive reviews in the field of gastrointestinal (GI) physiology, guiding readers on a journey through the complete digestive tract, while also highlighting related organs and glandular systems.It is not solely limited to organ system physiology, and related disciplines like anatomy and histology, but also examines the molecular and cellular processes that keep the digestive system running.As such, the book provides extensive information on the molecular, cellular, tissue, organ, and system levels of functions in the GI system. Chapters on the roles of the gut as an endocrine, exocrine and neural organ, as well as its microbiome functions, broaden readers’ understanding of the multi-organ networks in the human body.To help illustrate the interconnections between the physiological concepts, principles and clinical presentations, it outlines clinical examples such as pathologies that link basic science with clinical practice in special “clinical correlates” sections.Covering both traditional and contemporary topics, it is a valuable resource for biomedical students, as well as healthcare and scientific professionals.

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  • Interface between Regulation and Statistics in Drug Development
    Interface between Regulation and Statistics in Drug Development

    With the critical role of statistics in the design, conduct, analysis and reporting of clinical trials or observational studies intended for regulatory purposes, numerous guidelines have been issued by regulatory authorities around the world focusing on statistical issues related to drug development.However, the available literature on this important topic is sporadic, and often not readily accessible to drug developers or regulatory personnel.This book provides a systematic exposition of the interplay between the two disciplines, including emerging themes pertaining to the acceleration of the development of pharmaceutical medicines to serve patients with unmet needs.Features: Regulatory and statistical interactions throughout the drug development continuum The critical role of the statistician in relation to the changing regulatory and healthcare landscapes Statistical issues that commonly arise in the course of drug development and regulatory interactions Trending topics in drug development, with emphasis on current regulatory thinking and the associated challenges and opportunities The book is designed to be accessible to readers with an intermediate knowledge of statistics, and can be a useful resource to statisticians, medical researchers, and regulatory personnel in drug development, as well as graduate students in the health sciences.The authors’ decades of experience in the pharmaceutical industry and academia, and extensive regulatory experience, comes through in the many examples throughout the book.

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  • Regulation in India: Design, Capacity, Performance
    Regulation in India: Design, Capacity, Performance

    The rise of the regulatory state has been a major feature of modern constitutional democracies.India, the world’s largest democracy, is no exception to this trend.This book is the first major study of regulation in India.It considers how the development of regulation in India has altered the nature and functions of the state; how it is reshaping the relationship between business and the state; how it has called for the refashioning of established legal principles; and how it has raised new questions about the relationship between technical expertise and the rule of law.The chapters cover topics ranging from the foundations of the Indian regulatory state to the form of regulation across different sectors to regulation in practice.Together, the chapters reveal the challenges, promise, and limitations offered by contemporary regulatory practices, and they capture the close if sometimes fraught relationship that regulation must inevitably share with the political economy and constitutional schema within which it operates.

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  • Affect Regulation, Mentalization and the Development of the Self
    Affect Regulation, Mentalization and the Development of the Self

    In a brilliant examination of the frontiers of human emotion and cognition, four prominent psychoanalysts combine the perspectives of developmental psychology, attachment theory and psychoanalytic technique.The result of this marriage of disciplines is a bold, energetic and ultimately encouraging vision for the psychoanalytic treatment.

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  • Securities Regulation
    Securities Regulation

    This is the nation’s first and oldest casebook on securities regulation.This edition has been streamlined for easier use, but it continues to provide instructors and students with the full range of tools for the in-depth study of securities regulation.It has been revised and updated to take into account the following:Initial coin offerings and sales of other crypto-assetsChanges in the primary and secondary capital markets, including high frequency tradingCertain amendments to the public disclosure requirementsAmendments to the limited offering exemptionsThe ongoing debate around elements of Rule 10b–5Regulation Best InterestRecent Supreme Court cases, including their implications for certain civil litigation and the SEC’s continued reliance on administrative proceedings

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